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pentobarbital will minimize the extent or influence of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will lower the level or impact of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases levels of toremifene by impacting hepatic/intestinal enzyme CYP3A